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Prepare urea-hydrogen peroxide crystalline adduct - YouTube
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Hydrogen peroxide - urea (also called Hyperol or artizone) is a solid composed of equal amounts of hydrogen peroxide and urea. This compound is a white crystalline solid, which dissolves in water to give free hydrogen peroxide. Often called carbamide peroxide in the dental applications, it is used as a source of hydrogen peroxide for bleaching, disinfection, and oxidation. Hydrogen peroxide - urea contains solid and water-free hydrogen peroxide, which offers a higher stability and better controllability than liquid hydrogen peroxide when used as oxidizing agent.


Video Hydrogen peroxide - urea



Production

For the preparation of the compound, urea (which is stable to oxidizing agents such as hydrogen peroxide) is dissolved in 30% hydrogen peroxide (molar ratio 2:3) at temperatures below 60 °C. On cooling, hydrogen peroxide - urea precipitates in the form of small platelets.

Determination of the hydrogen peroxide content by titration with potassium permanganate solution gives a value of 35.4% which corresponds to 97.8% of the theoretical maximum value. The remaining impurity consists of urea.

The adduct can be stabilized by adding about 1% sodium pyrophosphate, sodium hexametaphosphate, dihydroxybutanedioic acid or EDTANa2, since these complex the catalytically active heavy metal ions.

Akin to water of crystallization, hydrogen peroxide cocrystallizes with urea with the stoichiometry of 1:1. The compound is simply produced (on a scale of several hundred tonnes a year) by the dissolution of urea in excess concentrated hydrogen peroxide solution, followed by crystallization. The laboratory synthesis is analogous.


Maps Hydrogen peroxide - urea



Structure and properties

Hydrogen peroxide-urea is a readily water-soluble, odorless, crystalline solid, which is available as white powder or colorless needles or platelets. Upon dissolving in various solvents, the 1:1 complex dissociates back to urea and hydrogen peroxide. So just like hydrogen peroxide, the (erroneously) so-called adduct is an oxidizer but the release at room temperature in the presence of catalysts proceeds in a controlled manner, thus the compound is suitable as a safe substitute for the unstable aqueous solution of hydrogen peroxide. Because of the tendency for thermal decomposition, which accelerates at temperatures above 82 °C, it should not be heated above 60 °C, particularly in pure form.

The solubility of commercial samples varies from 0.05 g/mL to more than 0.6 g/mL. The solid state structure of this adduct at the right has been determined by neutron diffraction.


Hydrazine
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Applications

Disinfectant and bleaching agent

Hydrogen peroxide - urea is mainly used as a disinfecting and bleaching agent in cosmetics and pharmaceuticals. As a drug, this compound is used in some preparations for the whitening of teeth. It is also used to relieve minor inflammation of gums, oral mucosal surfaces and lips including canker sores and dental irritation, and to emulsify and disperse earwax.

Carbamide peroxide is also suitable as a disinfectant, e.g. for germ reduction on contact lens surfaces or as an antiseptic for mouthwashes, ear drops or for superficial wounds and ulcers.

Reagent in organic synthesis

In the laboratory, it is used as a more easily handled replacement for hydrogen peroxide. It has proven to be a stable, easy-to-handle and effective oxidizing agent which is readily controllable by a suitable choice of the reaction conditions. It delivers oxidation products in a environmentally friendly manner and often in high yields especially in the presence of organic catalysts such as cis-butenedioic anhydride or inorganic catalysts such as sodium tungstate.

It converts thiols selectively to disulfides, secondary alcohols to ketones, sulfides to sulfoxides and sulfones, nitriles to amides, N-heterocycles to aminoxides,

aromatic hydroxyaldehydes to divalent phenols (Dakin reaction) and gives under suitable conditions the corresponding benzoic acids.

It oxidizes ketones to esters, in particular cyclic ketones, such as substituted cyclohexanones or cyclobutanones to give lactones (Baeyer-Villiger oxidation).

The epoxidation of various alkanes in the presence of benzonitrile yields oxiranes in yields of 79 to 96%.

The oxygen atom transferred to the alkene originates from the peroxoimide acid formed intermediately from benzonitrile. The resulting imidic acid tautomerizes to the benzamide.


Chemical Oxygen Generation | Respiratory Care
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Safety

The compound acts as a strong oxidizing agent and can cause skin irritation and severe eye damage.


Chemkart | Online platform for selling and buying chemicals
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See also

  • Sodium percarbonate

Hydrazine
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References


Extraction of Lotus Fibers | Open Science
src: rsos.royalsocietypublishing.org


External links

  • "Hydrogen peroxide urea adduct, UHP". Organic Chemistry Portal. 
  • "Carbamide Peroxide Monograph". Drugs.com. 

Source of the article : Wikipedia

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